Solving problems in genetics / Richard Kowles.
"The principle objective of this book is to help undergraduate students in the analysis of genetic problems. Many students have a great deal of difficulty doing genetic analysis, and the book will be useful regardless of which genetics text is being used. Most texts provide some kinds of proble...
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| Format: | Book |
| Language: | English |
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New York :
Springer,
[2006]
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Table of Contents:
- Preface
- 1. Mendelism
- Basic Probability: Methods for Analyzing Mendelian Genetics
- Forked Line Method
- Mendel's Data
- Crosses Involving Three or More Gene Pairs
- Goodness of Fit Testing
- Subdividing Chi Square
- Gene Interaction
- Distinguishing Among Genetic Ratios
- Double Fertilization in Plants
- Additional Plant Genetics Considerations
- 2. Sex Determination and Sex Linkage
- General Aspects of Mating Systems
- XX/XY Chromosome System
- Sex Ratios
- Binomial Statistics
- Haploid-Diploid Sex Determination
- Sex Linkage
- Pedigrees
- Partial Sex-Linkage
- 3. Chromosomes and Cell Division
- Chromosomes
- The Cell Cycle
- Further Analysis of the Cell Cycle
- Percent Labeled Mitoses Method
- Mitosis
- Meiosis
- Genetic Diversity
- C Values
- 4. Linkage, Recombination, and Mapping
- Exceptions to Independent Assortment
- Recombination Values and Genetic Maps
- Three-Point Tests
- Mapping Concepts
- Recombination Calculated With F[subscript 2] Data
- Haploid Genetics
- Tetrad Analysis
- Tetrad Analysis and Gene Mapping
- 5. Variations in Chromosome Number and Structure
- Types of Chromosome Variation
- Aneuploidy
- Polyploidy
- Deletions and Duplications
- Inversions
- Translocations
- Other Aberrations
- 6. Quantitative Inheritance
- Continuous Variation
- Polygenes
- Estimating Number of Gene Pairs Involved in Quantitative Traits
- Variance
- Broad Sense Heritability
- Narrow Sense Heritability
- Heterosis
- Thresholds
- Mapping Quantitative Traits
- 7. Population Genetics
- Concept of Gene Pools
- Gene and Genotype Frequencies
- Hardy-Weinberg Principle
- Hardy-Weinberg Equilibrium
- Extensions of Hardy-Weinberg Relationships
- Genetic Drift
- Migration
- Mutation
- Selection
- A Statistical Approach to Change in a Population
- Nonrandom Mating
- 8. Gene Concepts
- One-Gene One-Enzyme
- Allelism
- Bacterial Genetics
- Bacteriophages
- Complementation
- Genetic Fine Structure Analysis in Bacteriophages
- Genetic Fine Structure Analysis in Other Organisms
- 9. Molecular Basis of Heredity
- Nucleic Acids
- Nearest Neighbor Frequency Analysis
- Central Dogma
- Semiconservative Mode of Replication
- Replication Forks and Okazaki Fragments
- Transcription
- Proteins
- Translation
- Genetic Code
- Regulation
- Operon Systems
- Mutation
- Mutation Detection
- 10. Non-Mendelian Inheritance
- Cytoplasmic Inheritance
- Male Sterility in Plants
- Maternal Effects
- Genomic Imprinting
- DNA Trinucleotide Repeats
- Meiotic Drive
- B Chromosomes
- 11. Human Genetics
- Mendelian Inheritance in Humans
- Bias of Ascertainment
- Epidemiology and Pedigrees
- Linkage Analysis - Classical Approaches
- Physical Mapping
- Human Genome Project
- Population Genetics
- Testing Inheritance of a Single Allelic Pair in a Population
- Consanguinity
- Methods of Studying the Genetic Basis of Behavior in Humans
- 12. Additional Genetic Analysis Using Statistics
- More Probability
- Permutations and Combinations
- The Binomial Distribution
- Poisson Distribution
- Contingency Tables - Test for Independence
- Index.