Understanding nicotine and tobacco addiction / [editors, Gregory Bock and Jamie Goode].

"This book cover basic issues concerning the nature of the worldwide health problem posed by cigarette smoking and explore the psychoydnamics of cigarette addiction._The basic pharmacology and biochemistry of nicotine and its effect on the brain are reviewed here. The roles of different nicotin...

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Bibliographic Details
Corporate Author: Symposium on Understanding Nicotine and Tobacco Addiction Novartis Foundation
Other Authors: Bock, Gregory (Editor), Goode, Jamie (Editor)
Format: Book
Language:English
Published: Chichester, UK ; Hoboken, NJ : John Wiley & Sons, 2006.
Series:Novartis Foundation symposium ; 275.
Subjects:
Online Access:Contributor biographical information

MARC

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111 2 |a Symposium on Understanding Nicotine and Tobacco Addiction  |d (2005 :  |c Novartis Foundation) 
245 1 0 |a Understanding nicotine and tobacco addiction /  |c [editors, Gregory Bock and Jamie Goode]. 
264 1 |a Chichester, UK ;  |a Hoboken, NJ :  |b John Wiley & Sons,  |c 2006. 
300 |a viii, 275 pages :  |b illustrations ;  |c 23 cm. 
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490 1 |a Novartis Foundation symposium ;  |v 275 
500 |a Symposium held at the Novartis Foundation, London, 17-19 May 2005. 
504 |a Includes bibliographical references and index. 
505 0 |a The hazards of smoking and the benefits of stopping / Richard Peto, Richard Doll -- Animal models for nicotine dependence / Ian Stolerman -- Defining and assessing nicotine dependence in humans / Robert West -- Nicotinic acetylcholine receptor functions in the CNS investigated with a novel method of stereotaxic gene re-expression in knockout mice / Uwe Maskos, Sylvie Granon, Philippe Faure, Jean-Pierre Changeux -- Nicotine-mediated activation of signal transduction pathways / Marina R. Picciotto -- Complementary roles for the accumbal shell and core in nicotine dependence / David Balfour -- The dopamine D3 system : new opportunities for dopamine-based reward / Christian Heidbreder -- Pathways and systems involved in nicotine dependence / Athina Markou -- Localizing tobacco dependence pathways with functional brain imaging / Arthur L. Brody -- Pharmacogenetic approaches to nicotine dependence treatment / Caryn Lerman -- Pharmacogenomics and smoking cessation / Robert Walton -- What limits the efficacy of current nicotine replacement therapies? / Peter Hajek -- Exploring behavioural mechanisms of nicotine replacement therapy for smoking cessation / Saul Shiffman, Stuart Ferguson, Deborah Scharf -- Modifying the metabolism of nicotine as a therapeutic strategy / Rachel F. Tyndale, Edward M. Sellers -- Challenges in discovery and development of pharmacotherapies for tobacco addiction / William A. Corrigall. 
520 |a "This book cover basic issues concerning the nature of the worldwide health problem posed by cigarette smoking and explore the psychoydnamics of cigarette addiction._The basic pharmacology and biochemistry of nicotine and its effect on the brain are reviewed here. The roles of different nicotine receptor subtypes and other neurotransmitter systems are discussed._Chapters analyse data on genetic factors in the susceptibility to nicotine addiction._In Western countries, cigarette smoking as an adult has a heritability of 30-50% and candidate genes have been identified that may contribute to addiction susceptibility. ; ; The book also covers various approaches to therapy._Structured behavioural support programmes aid cessation attempts as do a number of pharmacotherapies, most notably nicotine replacement treatments and bupropion._A continuing theme in the discussions throughout the book is how best to treat nicotine addiction, given that many smokers would like to stop smoking but are unable to do so because of their addiction.;"--Publisher description. 
588 |a Machine converted from AACR2 source record. 
650 0 |a Nicotine addiction  |v Congresses  |9 734362 
650 0 |a Tobacco use  |x Physiological aspects  |v Congresses  |9 768872 
650 0 |a Tobacco use  |x Psychological aspects  |v Congresses  |9 785774 
650 0 |a Smoking cessation  |v Congresses  |9 734367 
650 0 |a Nicotine  |x Mechanism of action  |9 733485 
650 2 |a Nicotine  |x pharmacokinetics  |9 360367 
650 2 |a Tobacco Use Disorder  |9 359360 
700 1 |a Bock, Gregory,  |e editor.  |9 235460 
700 1 |a Goode, Jamie,  |e editor.  |9 1030929 
830 0 |a Novartis Foundation symposium ;  |v 275.  |9 1030931 
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Contributor biographical information

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