Advances in rapid sex-steroid action : new challenges and new chances in breast and prostate cancers / Gabriella Castoria, Antimo Migliaccio, editors.
"Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally...
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| Other Authors: | , |
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| Format: | Ebook |
| Language: | English |
| Published: |
New York :
Springer,
[2012]
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| Subjects: | |
| Online Access: | Springer eBooks Table of contents |
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| 245 | 0 | 0 | |a Advances in rapid sex-steroid action : |b new challenges and new chances in breast and prostate cancers / |c Gabriella Castoria, Antimo Migliaccio, editors. |
| 264 | 1 | |a New York : |b Springer, |c [2012] | |
| 264 | 4 | |c ©2012 | |
| 300 | |a 1 online resource (xvii, 268 pages) : |b illustrations (some colour) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | 0 | |t Non-genomic Action of Steroid Hormones: More Questions than Answers / |r Antimo Migliaccio, Gabriella Castoria, Antonio Bilancio, Pia Giovannelli, Marzia Di Donato, Ferdinando Auricchio -- |t Breast Cancer: -- |t Breast cancer: -- |t Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling / |r Guillermo P. Vicent, Roser Zaurin, Cecilia Ballaré, A. Silvina Nacht, Roni H. G. Wright, Francois Le Dily et al. -- |t Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer / |r Sarah J. Parsons, Jessica E. Pritchard, Emily M. Fox, Margaret A. Shupnik -- |t Cross Talk Between ERα and Src Signaling and Its Relevance to ER Status and Hormone Responsiveness / |r Jun Sun, Wen Zhou, Zafar Nawaz, Joyce M. Slingerland -- |t Post-translational Modifications of ER Alpha in Rapid Estrogen’s Action / |r Muriel Le Romancer, Coralie Poulard, Stéphanie Sentis, Laura Corbo -- |t Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancer / |r Marina Ines Flamini, Angel Matias Sanchez, Xiao-Dong Fu, Tommaso Simoncini -- |t Unraveling the Role of GPER in Breast Cancer / |r Rosamaria Lappano, Marcello Maggiolini -- |t Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cells / |r Cheryl S. Watson, Dragoslava Zivadinovic, Yow-Jiun Jeng, Rebecca A. Alyea, Terumi Midoro-Horiuti, Randall Goldblum et al. -- |t Prostate Cancer: -- |t Prostate cancer: -- |t Differential Functions of Stromal and Epithelial Androgen Receptor in Prostate Cancer Before and After Castration Resistant Stage / |r S. Lee, K.- P. Lai, S. Yeh, C. Chang -- |t Role of Androgens and Androgen Receptor in Prostate Cancer: Genomic and Non-Genomic Actions / |r Sara Marchiani, Lara Tamburrino, Monica Muratori, Lorella Bonaccorsi, Gianni Forti, Elisabetta Baldi -- |t Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Action / |r Laurent Morel, Silvère Baron -- |t The IGF-I Axis in Prostate Cancer: The Role of Rapid Steroid Actions / |r Antonino Belfiore -- |t Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugs / |r Christophe Massard, Karim Fizazi -- |t New Tools for Steroid Receptor Analysis and Regulatory Networks: -- |t New tools for steroid receptor analysis and regulatory networks: -- |t Quantitative Visualization of Sex Steroid Receptor Functions: AR and ERα / |r Michael J. Bolt, Sean M. Hartig, Adam T. Szafran, Sanjay N. Mediwala, Marco Marcelli, Michael A. Mancini -- |t Micropatterned Surfaces as Tools for the Study of the Rapid Non-Genomic Actions of Steroid Receptors / |r Andrew C. B. Cato, Emmanuel Oppong, Sylwia Sekula-Neuner. |
| 520 | |a "Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers."--Publisher's website. | ||
| 538 | |a Mode of access: World Wide Web. | ||
| 588 | |a Based on print version record. | ||
| 588 | |a Machine converted from AACR2 source record. | ||
| 650 | 0 | |a Breast |x Cancer |x Endocrine aspects. | |
| 650 | 0 | |a Hormones, Sex |x Physiological effect |9 769898 | |
| 650 | 0 | |a Prostate |x Cancer |x Endocrine aspects. | |
| 650 | 2 | |a Breast Neoplasms |x drug therapy |9 362720 | |
| 650 | 2 | |a Breast Neoplasms |x etiology |9 356949 | |
| 650 | 2 | |a Gonadal Steroid Hormones |x therapeutic use |9 366829 | |
| 650 | 2 | |a Prostatic Neoplasms |x drug therapy |9 366828 | |
| 650 | 2 | |a Prostatic Neoplasms |x etiology |9 366827 | |
| 650 | 2 | |a Receptors, Steroid |9 364513 | |
| 700 | 1 | |a Castoria, Gabriella, |e editor. |9 1098709 | |
| 700 | 1 | |a Migliaccio, Antimo, |e editor. |9 1098710 | |
| 776 | 1 | |i Print version: |t Advances in rapid sex-steroid action |d New York : Springer, [2012] |w 2011941855 |w (OCoLC)756282229 |z 9781461417637 | |
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| 856 | 4 | 1 | |3 Table of contents |u http://catdir.loc.gov/catdir/enhancements/fy1316/2011941855-t.html |
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