Intracellular delivery : fundamentals and applications / Aleš Prokop, editor.
"This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small...
Saved in:
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| Format: | Ebook |
| Language: | English |
| Published: |
Dordrecht ; New York :
Springer,
[2011]
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| Series: | Fundamental biomedical technologies.
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| Subjects: | |
| Online Access: | Springer eBooks |
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| 245 | 0 | 0 | |a Intracellular delivery : |b fundamentals and applications / |c Aleš Prokop, editor. |
| 264 | 1 | |a Dordrecht ; |a New York : |b Springer, |c [2011] | |
| 264 | 4 | |c ©2011 | |
| 300 | |a 1 online resource (xix, 867 pages) : |b illustrations. | ||
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| 490 | 1 | |a Fundamental biomedical technologies | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | 0 | |t Mechanisms of Uptake and Targeting: -- |t Mechanisms of uptake and targeting: -- |t Mass Transport via Cellular Barriers and Endocytosis / |r Silvia Ferrati, Agathe K. Streiff, Srimeenakshi Srinivasan, Jenolyn F. Alexander, Nikhil Bhargava, Andrew M. Peters et al. -- |t Approaches to Achieving Sub-cellular Targeting of Bioactives Using Pharmaceutical Nanocarriers / |r Melani Solomon, Gerard G. M. D’Souza -- |t Delivery to Intracellular Targets by Nanosized Particles / |r Gillian Barratt -- |t The Potential and Current Progress of Internalizing Molecules in Targeted Drug Delivery / |r Jiehua Zhou, John J. Rossi -- |t Simulation Based Analysis of Nanocarrier Internalization: Exciting Challenges with a New Computational Tool / |r Béla Csukás, Mónika Varga, Aleš Prokop, Sándor Balogh -- |t Nanosized Drug Delivery Vectors and the Reticuloendothelial System / |r Lisa M. Kaminskas, Ben J. Boyd -- |t Membrane Crossover by Cell-Penetrating Peptides: Kinetics and Mechanisms – From Model to Cell Membrane Perturbation by Permeant Peptides / |r Isabel D. Alves, Nicolas Rodriguez, Sophie Cribier, Sandrine Sagan -- |t Nanocarrier Formulation: -- |t Nanocarrier formulation: -- |t Intracellular Delivery: A Multifunctional and Modular Approach / |r Rupa R. Sawant, Vladimir P. Torchilin -- |t Poly(Alkyl Cyanoacrylate) Nanosystems / |r Julien Nicolas, Christine Vauthier -- |t Amphiphilic Block Copolymer Based Nanocarriers for Drug and Gene Delivery / |r Xiao-Bing Xiong, Afsaneh Lavasanifar -- |t Stimuli-Responsive Polymersomes / |r Min-Hui Li -- |t Silica-Based Nanoparticles for Intracellular Drug Delivery / |r Sandrine Quignard, Sylvie Masse, Thibaud Coradin -- |t Magnetic Nanoparticles for Biomedicine / |r Ivo Šafařík, Kateřina Horská, Mirka Šafaříková -- |t Biosynthesis of Metallic Nanoparticles and Their Applications / |r Adam Schröfel, Gabriela Kratošová -- |t Nanocrystals: Production, Cellular Drug Delivery, Current and Future Products / |r Rainer H. Müller, Ranjita Shegokar, Sven Gohla, Cornelia M. Keck -- |t Processing and Scale-up of Polymeric Nanoparticles / |r Christine Vauthier, Kawthar Bouchemal -- |t Medical Applications: -- |t Magnetic Resonance Tracking of Stem Cells with Iron Oxide Particles / |r Eddy S. M. Lee, Brian K. Rutt, Nicholas M. Fisk, Shih-Chang Wang, Jerry Chan -- |t Nanoparticles for the Oral Administration of Cancer Therapies / |r Socorro Espuelas, Maite Agüeros, Irene Esparza, Juan M. Irache -- |t Nanoparticles for Photodynamic Therapy Applications / |r Régis Vanderesse, Céline Frochot, Muriel Barberi-Heyob, Sébastien Richeter, Laurence Raehm, Jean-Olivier Durand -- |t Nanoparticles Enhanced Hyperthermia / |r Qian Wang, Jing Liu -- |t Non-viral Gene Therapy / |r Jianxiang Zhang, Xiaohui Li, Liping Lou, Xiaodong Li, Yi Jia, Zhe Jin et al. -- |t Imaging of Nanoparticle Delivery Using Terahertz Waves / |r Joo-Hiuk Son, Seung Jae Oh, Jihye Choi, Jin-Suck Suh, Yong-Min Huh, Seungjoo Haam -- |t Calcium Phosphate and Calcium Phosphosilicate Mediated Drug Delivery and Imaging / |r O. A. Pinto, A. Tabaković, T. M. Goff, Y. Liu, J. H. Adair -- |t Intracellular Bacteria and Protozoa / |r Maria Jose Morilla, Eder Lilia Romero -- |t Gene Therapy in Bone Regeneration: A Summary of Delivery Approaches for Effective Therapies / |r Laura Rose, Ross Fitzsimmons, Tarek El-Bialy, Hasan Uludağ -- |t Nanoinformatics: Developing Advanced Informatics Applications for Nanomedicine / |r Victor Maojo, Miguel García-Remesal, Diana de la Iglesia, José Crespo, David Pérez-Rey, Stefano Chiesa et al. |
| 520 | |a "This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly upon existing conservative practices. This volume is a collection of authoritative reviews. In the introductory section we define the field (intracellular delivery). Then, the fundamental routes of nanodelivery devices, cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; at the academic and applied levels, are covered. The following section is dedicated to enhancing delivery via special targeting motifs followed by the introduction of different types of intracellular nanodelivery devices (e.g. a brief description of their chemistry) and ways of producing these different devices. Finally, we put special emphasis on particular disease states and on other biomedical applications, whilst diagnostic and sensing issues are also included.Intracellular delivery / therapy is a highly topical which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is great potential for targeted delivery with improved localized delivery and efficacy."--Publisher's website. | ||
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