Pathological potential of neuroglia : possible new targets for medical intervention / Vladimir Parpura, Alexei Verkhratsky, editors.

"Pathophysiological states, neurological and psychiatric diseases are almost universally considered from the neurocentric point of view, with neurons being the principal cellular element of pathological process. The brain homeostasis, which lies at the fulcrum of healthy brain function, the com...

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Bibliographic Details
Other Authors: Parpura, Vladimir, 1964- (Editor), Verkhratskiĭ, A. N. (Alekseĭ Nestorovich) (Editor)
Format: Ebook
Language:English
Published: New York : Springer, [2014]
Subjects:
Online Access:Springer eBooks
Contributor biographical information
Table of Contents:
  • General pathophysiology of neuroglia: neurological and psychiatric disorders as gliopathies / Alexei Verkhratsky and Vladimir Parpura
  • Ionic signaling in physiology and pathophysiology of astroglia / Alexei Verkhratsky and Vladimir Parpura
  • Pathophysiology of vesicle dynamics in astrocytes / Nina Vardjan, Maja Potokar, Matjaž Stenovec, Jernej Jorgačevski, Saša Trkov, Marko Kreft and Robert Zorec
  • Glial glutamate and metabolic transporters as a target for neurodegenerative therapy and biomarkers / Thomas Philips and Rita Sattler
  • Alexander disease and astrotherapeutics / Michael Brenner and Albee Messing
  • Role of astrocytes in central nervous system trauma / Christopher R. Dorsett and Candace L. Floyd
  • Astroglial and neuronal integrity during cortical spreading depolarization / Sergei A. Kirov
  • Crucial role for astrocytes in epilepsy / Peter Bedner and Christian Steinhäuser
  • Microglial biology in neuroinflammatory disease: pharmaco-industrial approach to target validation / Thomas Möller, Paul Dylan Wes and Dario Doller
  • The role of astrocytes in Huntington's disease / Michelle Gray
  • Amyotrophic lateral sclerosis: a glial perspective / Chiara F. Valori, Liliana Brambilla and Daniela Rossi
  • Neurodegeneration and neuroglia: emphasis on astroglia in Alzheimer's disease / Alexei Verkhratsky, Vladimir Parpura and José J. Rodríguez
  • Possible therapeutic targets in microglia / Mami Noda
  • Novel therapeutic approaches to malignant gliomas / Vishnu Anand Cuddapah and Harald Sontheimer
  • Hepatic encephalopathy: a primary neurogliopathy / Sharon DeMorrow and Roger F. Butterworth
  • Astroglia and severe mental illness: a role for glutamate microdomains / Dan Shan, Stefani Yates, Rosalinda C. Roberts and Robert E. McCullumsmith
  • Emerging roles for glial pathology in addiction / Kathryn J. Reissner and Peter W. Kalivas
  • Astroglial connexins as elements of sleep-wake cycle regulation and dysfunction / Xinhe Liu and Christian Giaume
  • Experimental treatment of acquired and inherited neuropathies / Robert Fledrich, Ruth M. Stassart and Michael W. Sereda
  • Satellite glial cells as a target for chronic pain therapy / Menachem Hanani and David C. Spray
  • Enteric glial cells: implications in gut pathology / Brian D. Gulbransen and Isola A.M. Brown.
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