Longevity genes : a blueprint for aging / Gil Atzmon, editor.
"The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on th...
Saved in:
| Other Authors: | |
|---|---|
| Format: | Ebook |
| Language: | English |
| Published: |
New York :
Springer,
[2015]
|
| Series: | Advances in experimental medicine and biology ;
v. 847. |
| Subjects: | |
| Online Access: | Springer eBooks Table of contents Publisher description |
MARC
| LEADER | 00000czm a2200000 i 4500 | ||
|---|---|---|---|
| 005 | 20221115142715.0 | ||
| 007 | cr cnu000|uu|| | ||
| 008 | 141121s2015 nyua ob 001 0 eng d | ||
| 010 | |z 2015933511 | ||
| 011 | |a Z3950 Search: @or @attr 1=7 "9781493924035" @attr 1=7 "9781493924042" | ||
| 011 | |a Z3950 Record: 1 of 18 | ||
| 020 | |a 1493924044 |q electronic bk. | ||
| 020 | |a 9781493924042 |q electronic bk. | ||
| 020 | |a 1493924036 |q Internet | ||
| 020 | |a 9781493924035 |q Internet | ||
| 035 | |a (EDS)EDS4532318 | ||
| 040 | |a NLM |b eng |e rda |c NLM |d YDXCP |d BTCTA |d YOM |d OCLCF |d MMU |d SUC |d DLC |d OCLCQ |d OCLCO |d OCLCA |d UKMGB |d EZC |d CASUM |d OCL |d Z5A | ||
| 042 | |a nlmcopyc | ||
| 050 | 4 | |a QP86 |b .L654 2015 | |
| 082 | 0 | 4 | |a 612.68 |2 23 |
| 099 | |a 612.68 LON | ||
| 245 | 0 | 0 | |a Longevity genes : |b a blueprint for aging / |c Gil Atzmon, editor. |
| 264 | 1 | |a New York : |b Springer, |c [2015] | |
| 264 | 4 | |c ©2015 | |
| 300 | |a 1 online resource (xi, 194 pages) : |b illustrations (chiefly colour). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in experimental medicine and biology, |x 0065-2598 ; |v volume 847 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Evolutionary genetic bases of longevity and senescence / Diddahally R. Govindaraju -- Candidate genes that affect aging through protein homeostasis / Yair Argon and Tali Gidalevitz -- Autophagy and aging / Nuria Martinez-Lopez, Diana Athonvarangkul and Rajat Singh -- A genetic view of the mitochondrial role in ageing: killing us softly / Liron Levin and Dan Mishmar -- GWAS and meta-analysis in aging/ longevity / Linda Broer and Cornelia M. van Duijn -- Exome and whole genome sequencing in aging and longevity / Erik B. van den Akker, Joris deelen, P. Eline Slagboom and Marian Beekman -- Models to explore genetics of human aging / David Karasik and Anne Newman -- Systems biology of aging / Kendra Bolt and Aviv Bergman -- Epigenetics of aging / Dan Ben-Avraham -- Index. | |
| 520 | |a "The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research"--Publisher's description. | ||
| 650 | 0 | |a Longevity |x Genetic aspects. |9 356174 | |
| 650 | 0 | |a Aging. |9 313552 | |
| 650 | 0 | |a Medicine. |9 353188 | |
| 650 | 0 | |a Human genetics. |9 318990 | |
| 650 | 0 | |a Bioinformatics. |9 313258 | |
| 650 | 0 | |a Biological models. |9 332122 | |
| 650 | 0 | |a Life expectancy. |9 320091 | |
| 700 | 1 | |a Atzmon, Gil, |e editor. |9 880631 | |
| 776 | 1 | 8 | |w (OCoLC)896787327 |w (OCoLC)1083388860 |w (OCoLC)1113659086 |w (OCoLC)1130898063 |
| 830 | 0 | |a Advances in experimental medicine and biology ; |v v. 847. |x 0065-2598. |9 225156 | |
| 856 | 4 | 0 | |u https://ezproxy.aut.ac.nz/login?url=https://link.springer.com/10.1007/978-1-4939-2404-2 |z Springer eBooks |x TEMPORARY ERM URL |
| 856 | 4 | 1 | |3 Table of contents |u https://www.loc.gov/catdir/enhancements/fy1702/2015933511-t.html |
| 856 | 4 | 2 | |3 Publisher description |u https://www.loc.gov/catdir/enhancements/fy1702/2015933511-d.html |
| 942 | |c EB |n 0 | ||
| 999 | |c 1410076 |d 1410076 | ||