Computational methods in analysis of gene regulation and protein interactions / Ron Shamir.

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Bibliographic Details
Other Authors: Shamir, Ron (Speaker)
Format: Streaming video
Language:English
Published: London : Henry Stewart Talks, 2012.
Series:Henry Stewart talks. Biomedical & life sciences collection. Protein homeostasis.
Subjects:
Online Access:Henry Stewart Talks: Biomedical & Life Sciences
Series
Table of Contents:
  • Contents: Finding regulatory motifs
  • Finding motifs using target sets of promoters
  • Problem definition
  • The Amadeus motif finding algorithm
  • Architecture, benchmark results and global analysis
  • Finding transcriptional programs and their regulatory motifs
  • Problem definition
  • The Allegro software for recovering transcriptional program
  • Results on yeast osmotic shock expression profiles
  • Recovering microRNA binding motifs from 3' UTRs using stem cell expression profiles
  • Discovering a novel motif pair in C. elegans
  • Utilizing network information
  • Using expression and protein interaction data
  • Problem definition and the Matisse algorithm
  • Demonstration of Matisse on yeast osmotic shock data
  • Comparison of Matisse to other algorithms
  • Demonstration of Matisse on human stem cell data
  • The pluripotency network
  • Using expression and protein interaction data with interaction confidence
  • The Cezanne algorithm
  • DNA damage response in yeast.
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