MARC

LEADER 00000ngm a2200000 a 4500
003 UkLoHST
005 20220203115400.0
006 m c
007 cr|cna|||a||||
007 vz|czazum
008 220104s2021 enk020||||||||o|||v|eng d
028 5 0 |a 5594  |b Henry Stewart Talks 
035 |a (HSTalks)HST5594 
040 |a HSTalks  |b eng  |d ATU 
100 1 |a Matharu, Navneet,  |u (University of California San Francisco, USA),  |e speaker 
245 1 0 |a Modulating gene expression to treat diseases /  |c Navneet Matharu. 
264 1 |a London :  |b Henry Stewart Talks,  |c 2021. 
300 |a 1 streaming video file (20 min.) :  |b color, sound. 
336 |a two-dimensional moving image  |b tdi  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
344 |a digital 
347 |a video file  |b MPEG-4 
490 1 |a The biomedical & life sciences collection,  |x 2056-452X 
500 |a Animated audio-visual presentation with synchronized narration. 
500 |a Title from title frames. 
505 0 |a Contents: Programmable DNA targeting modules -- Effector domain functions and possibilities -- Haploinsufficiency and its role in disease -- CRISPRa targeting strategy to rescue Sim1 obesity -- CRISPRa targeting strategy to treat Mc4r haploinsufficiency. 
538 |a Mode of access: World Wide Web. 
650 0 |a CRISPR (Genetics)  |9 377731 
650 0 |a Gene expression.  |9 318311 
650 0 |a Gene targeting.  |9 346436 
650 0 |a Gene therapy.  |9 318312 
650 0 |a Medical genetics.  |9 320612 
650 0 |a Molecular genetics.  |9 321005 
650 2 |a Basic Helix-Loop-Helix Transcription Factors. 
650 2 |a Clustered Regularly Interspaced Short Palindromic Repeats.  |9 518058 
650 2 |a CRISPR-Cas Systems.  |9 516598 
650 2 |a Gene Expression Regulation.  |9 515169 
650 2 |a Gene Targeting  |x methods.  |9 366523 
650 2 |a Genetic Diseases, Inborn  |x therapy.  |9 363914 
650 2 |a Haploinsufficiency. 
650 2 |a Loss of Function Mutation.  |9 521881 
650 2 |a Obesity  |x genetics.  |9 362460 
650 2 |a Obesity  |x therapy.  |9 362555 
650 2 |a Receptor, Melanocortin, Type 4.  |9 513525 
650 2 |a Repressor Proteins.  |9 513604 
650 2 |a Up-Regulation. 
830 0 |a Henry Stewart talks.  |p Biomedical & life sciences collection. 
856 4 0 |u http://ezproxy.aut.ac.nz/login?url=https://hstalks.com/bs/4844/  |z Henry Stewart Talks: Biomedical & Life Sciences 
942 |c SV 
999 |c 1689181  |d 1689181 
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