Academic Journal
DNA Modified with Boron–Metal Cluster Complexes [M(C2B9H11)2]—Synthesis, Properties, and Applications.
| Title: | DNA Modified with Boron–Metal Cluster Complexes [M(C2B9H11)2]—Synthesis, Properties, and Applications. |
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| Authors: | Olejniczak, Agnieszka B., Nawrot, Barbara, Leśnikowski, Zbigniew J. |
| Source: | International Journal of Molecular Sciences; Nov2018, Vol. 19 Issue 11, p3501, 1p, 9 Diagrams, 1 Chart |
| Abstract: | Together with tremendous progress in biotechnology, nucleic acids, while retaining their status as "molecules of life", are becoming "molecular wires", materials for the construction of molecular structures at the junction between the biological and abiotic worlds. Herein, we present an overview of the approaches for incorporating metal centers into nucleic acids based on metal–boron cluster complexes (metallacarboranes) as the metal carriers. The methods are modular and versatile, allowing practical access to innovative metal-containing DNA for various applications, such as nucleic acid therapeutics, electrochemical biosensors, infrared-sensitive probes, and building blocks for nanoconstruction. [ABSTRACT FROM AUTHOR] |
| Subject Terms: | NUCLEIC acids, BIOMOLECULES, ANTISENSE nucleic acids, BASE pairs, DEOXYURIDINE triphosphate |
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| ISSN: | 16616596 |
| DOI: | 10.3390/ijms19113501 |
| Database: | Complementary Index |
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