Academic Journal
Water-soluble Cu30 nanoclusters as a click chemistry catalyst for living cell labeling via azide-alkyne cycloaddition.
Title: | Water-soluble Cu |
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Authors: | Yang, Ge, Xie, Yali, Wang, Yaru, Tang, Ying, Chng, Leng Leng, Jiang, Fuyi, Du, Fanglin, Zhou, Xianfeng, Ying, Jackie Y., Yuan, Xun |
Source: | Nano Research; Jan2023, Vol. 16 Issue 1, p1748-1754, 7p |
Abstract: | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) have gained increasing interest in the selective labeling of living cells and organisms with biomolecules. However, their application is constrained either by the high cytotoxicity of Cu(I) ions or the low activity of CuAAC in the internal space of living cells. This paper reports the design of a novel Cu-based nanocatalyst, water-soluble thiolated Cu |
Subject Terms: | RING formation (Chemistry), AZIDE synthesis, CELL membranes, BIOCOMPATIBILITY, CATALYTIC activity, NANOSTRUCTURED materials |
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ISSN: | 19980124 |
DOI: | 10.1007/s12274-022-4821-5 |
Database: | Complementary Index |