Academic Journal

Role of calibration in uncertainty-based referral for deep learning.

Bibliographic Details
Title: Role of calibration in uncertainty-based referral for deep learning.
Authors: Zhang, Ruotao, Gatsonis, Constantine, Steingrimsson, Jon Arni
Source: Statistical Methods in Medical Research; May2023, Vol. 32 Issue 5, p927-943, 17p
Abstract: The uncertainty in predictions from deep neural network analysis of medical imaging is challenging to assess but potentially important to include in subsequent decision-making. Using data from diabetic retinopathy detection, we present an empirical evaluation of the role of model calibration in uncertainty-based referral, an approach that prioritizes referral of observations based on the magnitude of a measure of uncertainty. We consider several configurations of network architecture, methods for uncertainty estimation, and training data size. We identify a strong relationship between the effectiveness of uncertainty-based referral and having a well-calibrated model. This is especially relevant as complex deep neural networks tend to have high calibration errors. Finally, we show that post-calibration of the neural network helps uncertainty-based referral with identifying hard-to-classify observations. [ABSTRACT FROM AUTHOR]
Subject Terms: DEEP learning, ARTIFICIAL neural networks, CALIBRATION, DIABETIC retinopathy, IMAGE analysis
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ISSN: 09622802
DOI: 10.1177/09622802231158811
Database: Complementary Index