Academic Journal
The New Era of Therapeutic Strategies for the Treatment of Retinitis Pigmentosa: A Narrative Review of Pathomolecular Mechanisms for the Development of Cell-Based Therapies.
| Title: | The New Era of Therapeutic Strategies for the Treatment of Retinitis Pigmentosa: A Narrative Review of Pathomolecular Mechanisms for the Development of Cell-Based Therapies. |
|---|---|
| Authors: | Becherucci, Valentina, Bacci, Giacomo Maria, Marziali, Elisa, Sodi, Andrea, Bambi, Franco, Caputo, Roberto |
| Source: | Biomedicines; Oct2023, Vol. 11 Issue 10, p2656, 23p |
| Abstract: | Retinitis pigmentosa, defined more properly as cone–rod dystrophy, is a paradigm of inherited diffuse retinal dystrophies, one of the rare diseases with the highest prevalence in the worldwide population and one of the main causes of low vision in the pediatric and elderly age groups. Advancements in and the understanding of molecular biology and gene-editing technologies have raised interest in laying the foundation for new therapeutic strategies for rare diseases. As a consequence, new possibilities for clinicians and patients are arising due to the feasibility of treating such a devastating disorder, reducing its complications. The scope of this review focuses on the pathomolecular mechanisms underlying RP better to understand the prospects of its treatment using innovative approaches. [ABSTRACT FROM AUTHOR] |
| Subject Terms: | RETINITIS pigmentosa, RETINAL degeneration, LOW vision, MOLECULAR biology, RARE diseases, DISEASE prevalence |
| Copyright of Biomedicines is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| ISSN: | 22279059 |
| DOI: | 10.3390/biomedicines11102656 |
| Database: | Complementary Index |
Availability