CMOS capacitive sensors for lab-on-chip applications : a multidisciplinary approach / Ebrahim Ghafar-Zadeh, Mohamad Sawan.
"1.1 Overview of Lab-on-Chip Laboratory-on-Chip (Lo C) is a multidisciplinary approach used for the miniaturization, integration and automation of biological assays or procedures in analytical chemistry [1–3]. Biology and chemistry are experimental sciences that are continuing to evolve and dev...
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| Other Authors: | |
| Format: | Ebook |
| Language: | English |
| Published: |
Dordrecht ; London :
Springer,
c2010.
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| Series: | Analog circuits and signal processing series
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| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | "1.1 Overview of Lab-on-Chip Laboratory-on-Chip (Lo C) is a multidisciplinary approach used for the miniaturization, integration and automation of biological assays or procedures in analytical chemistry [1–3]. Biology and chemistry are experimental sciences that are continuing to evolve and develop new protocols. Each protocol offers step-by-step laboratory instructions, lists of the necessary equipments and required biological and/or chemical substances [4–7]. A biological or chemical laboratory contains various pieces of equipment used for performing such protocols and, as shown in Fig. 1.1, the engineering aspect of Lo C design is aiming to embed all these components in a single chip for single-purpose applications. 1.1.1 Main Objectives of Lo C Systems Several clear advantages of this technology over conventional approaches, including portability, full automation, ease of operation, low sample consumption and fast assays time, make Lo C suitable for many applications including. 1.1.1.1 Highly Throughput Screening To conduct an experiment, a researcher fills a well with the required biological or chemical analytes and keeps the sample in an incubator for some time to allowing the sample to react properly. Afterwards, any changes can be observed using a microscope. In order to quickly conduct millions of biochemical or pharmacolo- cal tests, the researchers will require an automated highly throughput screening (HTS) [8], comprised of a large array of wells, liquid handling devices (e.g., mic- channel, micropump and microvalves [9–11]), a fully controllable incubator and an integrated sensor array, along with the appropriate readout system."--Publisher's website. |
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| Item Description: | Description based on print version record. |
| Physical Description: | 1 electronic document (x, 146 p.) : ill. |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1282926586 9048137276 9781282926585 9789048137275 |