Diverse effects of hypoxia on tumor progression / M. Celeste Simon, editor.
"Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though addition...
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Corporate Author: | |
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Other Authors: | |
Format: | Ebook |
Language: | English |
Published: |
Heidelberg ; New York :
Springer,
c2010.
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Series: | Current topics in microbiology and immunology
v. 345. |
Subjects: | |
Online Access: | Springer eBooks |
Summary: | "Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance. Hypoxia promotes cancer progression by regulating various aspects of cancer biology, including radiotherapy resistance, metabolism, angiogenesis and invasion/migration"--Publisher's website. |
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Item Description: | Description based on print version record. |
Physical Description: | 1 electronic document. |
Format: | Mode of access: World Wide Web. |
Bibliography: | Includes bibliographical references and index. |
ISBN: | 1282979760 3642133290 9781282979765 9783642133299 |
ISSN: | 0070-217X ; |