DNA methylation, epigenetics, and metastasis / edited by Manel Esteller.
"This book provides a broad and rich outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. It describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the hum...
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| Other Authors: | |
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| Format: | Ebook |
| Language: | English |
| Published: |
Dordrecht ; New York :
Springer,
[2005]
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| Series: | Cancer metastasis (Series) ;
v. 7. |
| Subjects: | |
| Online Access: | Springer eBooks Table of contents Publisher description |
| Summary: | "This book provides a broad and rich outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. It describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour. It also provides a comprehensive insightful look at the molecular players involved in DNA methylation, histone modification and chromatin remodelling complexes causing epigenetic lesions linked to the metastasic phenotypes."--Jacket |
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| Physical Description: | 1 online resource (xi, 310 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1402036418 9781402036415 1280284129 9781280284120 1402036426 9781402036422 |