Intramembrane-cleaving proteases (I-CLiPs / edited by Nigel M. Hooper and Uwe Lendeckel.
"In recent years a growing number of proteases have been identified that catalyse peptide bond hydrolysis in the plane of the cellular membrane. These so-called ‘intramembrane-cleaving proteases’ (I-CLi Ps) are involved in a diverse range of cellular processes, including cell regulation, signal...
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| Corporate Author: | |
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| Other Authors: | , |
| Format: | Ebook |
| Language: | English |
| Published: |
Dordrect, Netherlands :
Springer,
c2007.
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| Series: | Proteases in biology and disease ;
v. 6. |
| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | "In recent years a growing number of proteases have been identified that catalyse peptide bond hydrolysis in the plane of the cellular membrane. These so-called ‘intramembrane-cleaving proteases’ (I-CLi Ps) are involved in a diverse range of cellular processes, including cell regulation, signalling, quorum sensing, protein processing, lipid metabolism and the unfolded protein response. Some I-CLi Ps play critical roles in diseases such as Alzheimer’s and viral infection. The authors, who are all world leaders in this exciting field of cell biology, provide an overview of the various proteases including recent data derived from the structural determination of some of the I-Cli Ps, and discuss the various roles that these proteases play in biology and disease. The aim of this book is to provide an update on this emerging group of unusual but important proteases for both the specialist and those with a broader interest in proteases. Amongst the target audience will be protease researchers, enzymologists, those working in academia and the pharmaceutical industry on biological processes and diseases involving I-CLi Ps."--Publisher's website. |
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| Item Description: | Description based on print version record. |
| Physical Description: | 1 electronic document. |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1280944064 1402063113 9781280944062 9781402063114 |