Polyploidization and cancer / edited by Randy Y.C. Poon.
"Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of ev...
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| Format: | Ebook |
| Language: | English |
| Published: |
New York : Austin, Tex. :
Springer Science+Business Media ; Landes Bioscience,
c2010.
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| Series: | Advances in experimental medicine and biology ;
v. 676. |
| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | "Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation. A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overviewsubjects relating to polyploidization and cancer."--Publisher's website. |
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| Item Description: | Description based on print version record. |
| Physical Description: | 1 electronic document. |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1283074419 1441961992 9781283074414 9781441961990 |