SuperMEN1 : pituitary, parathyroid and pancreas / edited by Katalin Balogh, Attila Patocs.

"The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings...

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Bibliographic Details
Corporate Author: SpringerLink ebooks - Biomedical and Life Sciences (2010)
Other Authors: Balogh, Katalin, 1977-, Patocs, Attila, 1973-
Format: Ebook
Language:English
Published: New York : Austin, Tex. : Springer Science+Business Media ; Landes Bioscience, c2009.
Series:Advances in experimental medicine and biology ; v. 668.
Subjects:
Online Access:Springer eBooks
Description
Summary:"The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type I syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgroundsofthis syndrome and to review carefully the latest discoveries concerning the possible functions and interactions ofmenin, the protein encoded by the MEN1gene,including itspossible role incell cycle regulation,hematopoiesis,and bone development. The goal ofthe book is also to present the most recent findings and the broadest aspects of the role of menin in tumorigenesis of the endocrine glands involved in MEN I syndrome (pituitary, parathyroid, endocrine pancreas and adrenal). The connection between the basic experimental and clinical points of view are highlighted through a discussion on animal models, which explores the field in both an inspiring and questioning manner with a focus on areas that remain to be clarified. Our goal was to bring together clinicians and basic researchers who represent a wide range of interests in this particular field of endocrine oncology. Presentingacomprehensive and current overviewofbasic experimental and clinical findings, this book can bring us closer to understanding endocrine tumorigenesis in multiple endocrine neoplasia Type I. Katalin Balogh, MD, Ph D Attita Patocs, MD, MSc, Ph D v ABOUT THEEDITORS. . ."--Publisher's website.
Item Description:Description based on print version record.
Physical Description:1 electronic document.
Format:Mode of access: World Wide Web.
Bibliography:Includes bibliographical references and index.
ISBN:1441916644
9781441916648
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