Current perspectives in microRNAs (miRNA) / editor Shao Yao Ying.
"Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode micro RNAs, which are respon...
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| Format: | Ebook |
| Language: | English |
| Published: |
[London?] :
Springer,
c2008.
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| Online Access: | Springer eBooks |
| Summary: | "Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode micro RNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. Micro RNAs (mi RNAs), small single-stranded 17–25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (m RNAs) that contain either complete or partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. Currently over 1000 native mi RNA species found in vertebrates and many more new mi RNA homologs continue to be identified; however, most of their functions remain to be determined. In this book, many new perspectives of the mi RNA research are reviewed and discussed, including their roles in stem cell maintenance, embryonic development, tissue differentiation, adult physiology, disease pathology, cancer research, viral infection, genetic engineering in plants, and utility in cosmetic applications. These new findings may not only provide significant insight into the various mechanisms of mi RNAs but also offer a great opportunity in developing new therapeutic interventions."--Publisher's website. |
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| Item Description: | Description based on print version record. |
| Physical Description: | 1 electronic document. |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1281773832 1402085338 9781281773838 9781402085338 |