Axonal branching and recovery of coordinated muscle activity after transection of the facial nerve in adult rats / D.N. Angelov [and others].
"Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this " post-paralytic syndrome" is the misdirected reinnervation of targets, which consists of two major components. First, due to malfunction...
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| Main Author: | |
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| Format: | Ebook |
| Language: | English |
| Published: |
Berlin ; New York :
Springer,
2005.
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| Series: | Advances in anatomy, embryology, and cell biology ;
180. |
| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | "Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this " post-paralytic syndrome" is the misdirected reinnervation of targets, which consists of two major components. First, due to malfunctioning axonal guidance, a muscle gets reinnervated by a " foreign" axon, that has been misrouted along a " wrong" fascicle. Second, the supernumerary collateral branches emerging from all transected axons simultaneously innervate antagonistic muscles and cause severe impairment of their coordinated activity. Since it is hardly possible to influence the first major component and improve the guidance of several thousands axons, the authors concentrated on the second major component and tried to reduce the collateral axonal branching."--Publisher's website. |
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| Physical Description: | 1 online resource (viii, 130 pages) : illustrations. |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1280337923 3540299319 9781280337925 9783540299318 |
| ISSN: | 0301-5556 ; |