Morphofunctional aspects of tumor microcirculation / Domenico Ribatti.
Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the tumor microenvironment. Like...
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| Format: | Ebook |
| Language: | English |
| Published: |
Dordrecht ; New York :
Springer,
[2012]
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| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | Blood vessels of tumors display many structural and functional abnormalities. Their unusual leakiness, potential for rapid growth and remodeling, and expression of distinctive surface molecules mediate the dissemination of tumor cells in the bloodstream and maintain the tumor microenvironment. Like normal blood vessels, they consist of endothelial cells, mural cells and their enveloping basement membrane. Common features, irrespective of their origin, size and growth pattern, are absent hierarchy, formation of large-caliber sinusoidal vessels, markedly heterogeneous density, increased permeabi. |
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| Physical Description: | 1 online resource : illustrations |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1283698102 9400749368 9781283698108 9789400749368 |