Molecular oncology testing for solid tumors : a pragmatic approach / Michael Ola Idowu, Catherine Isabelle Dumur, Carleton Theodore Garrett, editors.

This text is designed to present an up-to-date practical approach to molecular testing in an easy to understand format. Emphasis is placed on molecular testing for solid tumors, while underscoring the following: i) the crucial role of pathologists in ensuring specimen adequacy for molecular testing;...

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Bibliographic Details
Other Authors: Dumur, Catherine Isabelle (Editor), Garrett, Carleton T. (Editor), Idowu, Michael Ola (Editor)
Format: Ebook
Language:English
Published: Cham : Springer, 2015.
Series:Online access with purchase: Springer (t).
Subjects:
Online Access:Springer eBooks
Description
Summary:This text is designed to present an up-to-date practical approach to molecular testing in an easy to understand format. Emphasis is placed on molecular testing for solid tumors, while underscoring the following: i) the crucial role of pathologists in ensuring specimen adequacy for molecular testing; ii) current molecular assays/platforms (including next-generation sequencing); iii) clinical utility and limitations of biomarkers to enable effective communication with clinicians; iv) the importance of quality assurance metrics to ensure accurate and reproducible results; v) pitfalls in test interpretation (that may lead to False Positive or False Negative interpretations); vi) importance of using standard nomenclature, including exercises on variant (mutation) description; vii) regulatory affairs, coding and reimbursement. The uniqueness of this text is the use of a standardized template for each of the molecular tests being discussed followed by a discussion of relevant quality assurance issues to ensure focused and efficient presentation of information. Molecular Oncology Testing for Solid Tumors will enable readers to easily understand the Ordering, Processing, Interpretation, Reporting and the clinical Application (OPIRA) process of molecular testing or biomarkers.
Item Description:Includes index.
Physical Description:1 online resource (ix, 742 pages) : illustrations (some colour).
Format:Mode of access: World Wide Web.
ISBN:3319163043
9783319163048
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