Defects in T cell trafficking and resistance to cancer immunotherapy / Emmanuel Donnadieu, editor.
"This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to t...
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| Other Authors: | |
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| Format: | Ebook |
| Language: | English |
| Published: |
Switzerland :
Springer,
[2016]
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| Series: | Resistance to targeted anti-cancer therapeutics ;
v. 9. |
| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | "This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy."--Publisher's website. |
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| Physical Description: | 1 online resource (viii, 199 pages) : illustrations. |
| Format: | Mode of access: World Wide Web. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 3319422235 9783319422237 |
| ISSN: | 2196-5501 ; |