Current immunotherapeutic strategies in cancer / Matthias Theobald, editor.
"This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), i...
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| Other Authors: | |
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| Format: | Ebook |
| Language: | English |
| Published: |
Cham, Switzerland :
Springer,
[2020]
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| Series: | Recent results in cancer research ;
214. |
| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | "This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific mAbs as novel treatment options for leukemia and solid tumors. It also examines the advances toward personalized immunotherapy, focusing on the effectiveness of adoptive cell therapy using genetically engineered T cells with tumor-associated antigen-specific T-cell receptors and chimeric antigen receptors, as well as the role of tailored vaccines based on the patient's cancer mutanome. Further, it describes the impressive therapeutic results recently achieved with checkpoint inhibitors, and analyzes novel strategies to modulate the immunosuppressive tumor microenvironment"--Publisher's description. |
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| Physical Description: | 1 online resource (v, 187 pages) : illustrations (some colour). |
| Bibliography: | Includes bibliographical references. |
| ISBN: | 3030237648 9783030237646 3030237656 9783030237653 |
| ISSN: | 2197-6767 ; |