Multiscale modeling of vascular dynamics of micro- and nano-particles : application to drug delivery system / Huilin Ye, Zhiqiang Shen and Ying Li.
Recent advances in this exciting field see the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance efficacy and specificity, the control and guidance of drug carriers in vasculature become crucial. The current...
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| Main Authors: | , , |
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| Format: | Ebook |
| Language: | English |
| Published: |
San Rafael [California] (40 Oak Drive, San Rafael, CA, 94903, USA) :
Morgan & Claypool Publishers,
[2019]
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| Series: | IOP concise physics.
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| Subjects: | |
| Online Access: | Click here to view this book |
| Summary: | Recent advances in this exciting field see the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance efficacy and specificity, the control and guidance of drug carriers in vasculature become crucial. The current bottlenecks in the optimal design of drug-carrying particles are lack of knowledge about the transport of particles, adhesion on the endothelium wall, and subsequent internalization into diseased cells. To study the transport and adhesion of particles in vasculature, the authors of this book have made great effort to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This text discusses the recent achievements from the establishment of fundamental physical problems to the development of a multiscale model and, finally, large-scale simulations for understanding the transport of particle-based drug carriers in blood flow. |
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| Item Description: | "Version: 20191201"--Title page verso. Title from PDF title page (viewed on January 6, 2020). |
| Physical Description: | 1 online resource : illustrations (some colour). |
| Bibliography: | Includes bibliographical references. |
| ISBN: | 1643277928 9781643277929 |
| ISSN: | 2053-2571 |