Myosins : a Superfamily of Molecular Motors / edited by Lynne M. Coluccio.
Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. My...
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| Other Authors: | |
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| Format: | Ebook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint : Springer,
2020.
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| Edition: | 2nd ed. 2020. |
| Series: | Advances in experimental medicine and biology ;
1239. |
| Subjects: | |
| Online Access: | Springer eBooks |
| Summary: | Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact. Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles. |
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| Physical Description: | 1 online resource (xi, 455 pages 116 illustrations, 97 illustrations in color). |
| ISBN: | 3030380610 9783030380618 3030380629 9783030380625 |
| ISSN: | 0065-2598 ; |