Stochastic dynamics in computational biology / Stefanie Winkelmann, Christof Schütte.

The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another ma...

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Bibliographic Details
Main Authors: Winkelmann, Stefanie (Author), Schütte, Christof (Author)
Format: Ebook
Language:English
Published: Cham : Springer, 2020.
Series:Frontiers in applied dynamical systems.
Subjects:
Online Access:Springer eBooks
Description
Summary:The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems.
Physical Description:1 online resource.
ISBN:3030623866
9783030623869
3030623874
9783030623876
ISSN:2364-4532
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