Fast quantitative magnetic resonance imaging / Guido Buonincontri, Joshua Kaggie and Martin Graves.

"Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challeng...

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Bibliographic Details
Main Authors: Buonincontri, Guido (Author), Graves, Martin J. (Author), Kaggie, Joshua D. (Author)
Format: Ebook
Language:English
Published: Cham, Switzerland : Springer, [2020]
Series:Synthesis lectures on biomedical engineering ; #59.
Subjects:
Online Access:Springer Nature Synthesis Collection of Technology (R0) eBook Collection 2020
Description
Summary:"Among medical imaging modalities, magnetic resonance imaging (MRI) stands out for its excellent soft-tissue contrast, anatomical detail, and high sensitivity for disease detection. However, as proven by the continuous and vast effort to develop new MRI techniques, limitations and open challenges remain. The primary source of contrast in MRI images are the various relaxation parameters associated with the nuclear magnetic resonance (NMR) phenomena upon which MRI is based. Although it is possible to quantify these relaxation parameters (q MRI) they are rarely used in the clinic, and radiological interpretation of images is primarily based upon images that are relaxation time weighted. The clinical adoption of q MRI is mainly limited by the long acquisition times required to quantify each relaxation parameter as well as questions around their accuracy and reliability. More specifically, the main limitations of q MRI methods have been the difficulty in dealing with the high inter-parameter correlations and a high sensitivity to MRI system imperfections.Recently, new methods for rapid q MRI have been proposed. The multi-parametric models at the heart of these techniques have the main advantage of accounting for the correlations between the parameters of interest as well as system imperfections. This holistic view on the MR signal makes it possible to regress many individual parameters at once, potentially with a higher accuracy. Novel, accurate techniques promise a fast estimation of relevant MRI quantities, including but not limited to longitudinal (T1) and transverse (T2) relaxation times. Among these emerging methods, MR Fingerprinting (MRF), synthetic MR (sy MRI or MAGIC), and T1‒T2 Shuffling are making their way into the clinical world at a very fast pace. However, the main underlying assumptions and algorithms used are sometimes different from those found in the conventional MRI literature, and can be elusive at times. In this book, we take the opportunity to study and describe the main assumptions, theoretical background, and methods that are the basis of these emerging techniques.Quantitative transient state imaging provides an incredible, transformative opportunity for MRI. There is huge potential to further extend the physics, in conjunction with the underlying physiology, toward a better theoretical description of the underlying models, their application, and evaluation to improve the assessment of disease and treatment efficacy."--Publisher's website.
Item Description:Title from PDF title page (viewed on February 28, 2020).
Physical Description:1 online resource (xv, 124 pages) : illustrations (some colour).
Bibliography:Includes bibliographical references.
ISBN:1681736942
1681736950
1681736969
3031000463
303101667X
9781681736945
9781681736952
9781681736969
9783031000461
9783031016677
ISSN:1930-0336 ;
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