Innate immunity, inflammation and cancer : from bench to bedside / Alberto Mantovani.
The innate immune system includes a cellular and a humoral arm. Tumor-associated macrophages (TAM) have served as a paradigm for the importance of the tumor microenvironment in tumor progression. Single cell analysis and spatial transcriptomics have provided new vistas on the complexity and function...
Saved in:
| Other Authors: | |
|---|---|
| Format: | Streaming video |
| Language: | English |
| Published: |
London :
Henry Stewart Talks,
2024.
|
| Series: | Henry Stewart talks. Biomedical & life sciences collection.
|
| Subjects: | |
| Online Access: | Henry Stewart Talks: Biomedical & Life Sciences |
| Summary: | The innate immune system includes a cellular and a humoral arm. Tumor-associated macrophages (TAM) have served as a paradigm for the importance of the tumor microenvironment in tumor progression. Single cell analysis and spatial transcriptomics have provided new vistas on the complexity and function of TAM. Moreover, myeloid cells are a source of fluid phase pattern recognition molecules (ante-antibodies) and, in turn, humoral innate immunity shapes recruitment and function of these cells. TAM engage in complex bidirectional interactions with innate and adaptive lymphoid cells and stroma. Moreover, they play an important role in response and resistance to current immunotherapy approaches. Prof. Mantovani discusses how myeloid cells represent tools and targets for innovative therapeutic approaches, complementing current strategies.. |
|---|---|
| Item Description: | Title from title frames. Webinar. |
| Physical Description: | 1 streaming video file (1 hr., 9 min.) : colour, sound |
| Playing Time: | 01:09:00 |
| Format: | Mode of access: World Wide Web. |
| ISSN: | 2056-452X |